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Life & medical sciences · OECD FoS 3.2 · China MoE 100207 影像医学与核医学

Medical imaging & pathology

医学影像与病理

L3Systemic transformation → Steady Score 2.80 · Last reviewed 2026-10-21 · Next review 2026-12-20

BIGGEST BREAKTHROUGH 2026-01 Field leapAI · major

MASAI final results: AI-supported screening non-inferior on interval cancers, sensitivity 80.5% vs 73.8% (The Lancet) ↗

RCT of 105,934 women shows non-inferiority on the hard endpoint of interval cancers

Why this level

Imaging is medicine's most AI-penetrated branch: radiology dominates FDA's AI device list; the MASAI RCT showed AI-supported mammography safely cut reading workload by ~44% (Lancet Oncology 2023).

Research method 3Scientific discovery 3Practitioner adoption 3Education & curriculum 1
Research method ×0.33/4

Deep learning is the mainstream method in imaging and pathology research · source ↗

Scientific discovery ×0.353/4

Several large randomised trials confirm AI-assisted screening is feasible; the final MASAI results were published in The Lancet (2026) · source ↗

Practitioner adoption ×0.253/4

Radiology accounts for most FDA AI devices, and screening programmes in several European countries have adopted AI · source ↗

Education & curriculum ×0.11/4

No public evidence of residency-training reform

S = 0.30·method + 0.35·discovery + 0.25·adoption + 0.10·education (education scores 0 when there is no evidence; if empty, the other weights are renormalised)

Sources

Composite 2.5–3.49 (or ≥3.5 with any of method/discovery/adoption below 3): AI is standard infrastructure with multiple independent breakthroughs. All levels →

Research directions

Screening & triagePathology foundation modelsReport generation

Papers

Milestones 9· 1 leaps

Big glowing nodes are leaps: AI leap cool · Field leap warm · double ring = both

  1. Model

    Sophont launches Holon-S1, a pan-cancer pathology model predicting spatial gene expression from H&E (research use)

    AI: vendor reports gains across 16 organs; Field: no clinical validation yet

    PR NewswireVendor claim
  2. Regulatory

    FDA list reaches 1,614 AI devices, mostly radiology

    1,614 AI devices on the FDA list

    FDA
  3. Clinical

    Manual, digital and AI TIL scoring: secondary analysis of the APHINITY RCT (Lancet Oncology)

    AI: AI pathology scoring benchmarked against manual scoring in a large RCT cohort; Field: trial-level evidence for standardising TIL biomarkers

    The Lancet OncologyTo be verified
  4. ClinicalField leap

    MASAI final results: AI-supported screening non-inferior on interval cancers, sensitivity 80.5% vs 73.8% (The Lancet)

    RCT of 105,934 women shows non-inferiority on the hard endpoint of interval cancers

    The LancetTo be verified
  5. Paper

    UNI: a general-purpose self-supervised model for computational pathology (Nature Medicine)

    Pathology foundation model beats prior methods on 30+ tasks

    Nature Medicine
  6. Clinical

    MASAI RCT: AI-supported mammography screening (Lancet Oncology)

    Interim RCT: 44% less reading workload, no drop in detection

    Lancet Oncology
  7. Paper

    International evaluation of an AI system for breast cancer screening (Nature)

    Fewer false positives and negatives than radiologists across two countries

    Nature
  8. Paper

    Dermatologist-level classification of skin cancer (Nature)

    Landmark paper that launched the medical-imaging AI wave

    Nature
  9. Paper

    Deep learning for diabetic retinopathy detection at ophthalmologist level (JAMA)

    Among the first to show specialist-level AI reading in a top medical journal

    JAMA
More papers & repos 6

Latest news 12

Data updated: AI × disciplines(UTC+8)