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AI × DISCIPLINES · L0 → L4

How far has AI transformed each discipline?

43 disciplines in 7 groups, rated from L0 (Not yet transformed) to L4 (AI-led) on four dimensions. Data as of 2026-10-22 (Beijing time). How levels are defined ↓

L0 Not yet transformed 3L1 Assistive 8L2 Local breakthroughs 23L3 Systemic transformation 9L4 AI-led 0

Recent leaps

AI leapa leap for AI itself · Field leapa leap for the discipline

Cybersecurity 2026-10-16 AI leap Claude traces the NIST elliptic-curve seeds to drand48 seeded with 1997–98 timestamps; bounty claimed ⓘ Vendor post, but bounty organiser Filippo Valsorda independently re-implemented and verified the seeds; bounty paid Mathematics 2026-10-11 AI leapField leap Banks: human-verified, explicit account of the OpenAI proof that Landau–Siegel zeros do not exist (arXiv 2610.15483) ⓘ Preprint, but it is itself a line-by-line verification by Banks; Kerr gave an independent simpler proof (arXiv 2610.21099) and the Lean formalisation was re-checked by two kernels; not yet journal-refereed Mathematics 2026-10-01 Field leap Song & Zhang prove the 31-year-old Kannan–Lovász–Simonovits conjecture with human-directed AI agents (arXiv 2610.01447); Bizeul–Klartag–Lehec give an independent proof built on their criterion (arXiv 2610.05474) ⓘ Preprint, but independently re-proved by Bizeul–Klartag–Lehec, who call the Song–Zhang criterion the crucial step (arXiv 2610.05474), plus another proof (arXiv 2610.07728) and a Lean 4 formalisation; AI role is self-reported, so AI impact is Major Archaeology & classics 2026-06-25 Field leap Vesuvius Challenge: first entire Herculaneum scroll read (PHerc. 1667, ~20 columns, ~1.5 m) Mathematics 2026-05-21 AI leap DeepMind formal proof-search agent autonomously resolves 9 of 353 open Erdős problems and 44/492 OEIS conjectures in Lean ⓘ Preprint, but all proofs are machine-checked in Lean Mathematics 2026-05-20 AI leapField leap Unit-distance conjecture disproved: an OpenAI general reasoning model constructs point sets with n^{1+ε} unit distances ⓘ Announced by OpenAI, but independently verified by nine outside mathematicians (arXiv 2605.20695) Mathematics 2026-05-20 Field leap “Remarks on the disproof of the unit distance conjecture”: human-verified, simplified proof by nine mathematicians ⓘ Preprint, but it is itself the independent verification by nine mathematicians Genomics & genetics 2026-03-04 AI leap Evo 2: 40B-parameter genome model with 1 Mb context across all domains of life (Nature) Medical imaging & pathology 2026-01 Field leap MASAI final results: AI-supported screening non-inferior on interval cancers, sensitivity 80.5% vs 73.8% (The Lancet) Life sciences (structural & molecular biology) 2025-11-05 AI leapField leap Atomically accurate de novo design of antibodies with RFdiffusion (Nature) Mathematics 2025-11-03 AI leap AlphaEvolve at scale: 67 problems, several best-known constructions improved; 11-D kissing number 592→593 ⓘ Peer-reviewed version published in PNAS on 2026-09-30 Cybersecurity 2025-08-08 AI leap DARPA AIxCC final: Team Atlanta wins; autonomous systems find ~80% of planted bugs and patch 60%+, all open-sourced
43disciplines tracked
9at L3 or L4
236milestones since 2025
258news items, last 14 days
22items to be verified

Progress matrix

Rows: groups · columns: levels · click a discipline for details

All disciplines

Vendor claim Life & medical sciences · OECD 1.6

Life sciences (structural & molecular biology)

L3Systemic transformation↑ Rising AI ×3Field ×5

L3 (close to L4): AlphaFold made structure prediction the default step and won the 2024 chemistry Nobel; RFdiffusion reported atomically accurate de novo antibodies (Nature 2025); Evo 2 (Nature, Mar 2026) models and designs genomes across life. Missing: independent adoption surveys and curriculum evidence.

Score 3.45Latest 2026-10-21Milestones 13News 12
Life & medical sciences · OECD 1.6

Genomics & genetics

L3Systemic transformation↑ Rising AI ×1

Deep-learning variant calling (DeepVariant) is in standard pipelines; AlphaMissense scores 71M missense variants (Science 2023); AlphaGenome reads 1 Mb of DNA to predict thousands of tracks (Nature, Jan 2026); genome LMs like Evo generate functional sequences.

Score 2.80Latest 2026-10-21Milestones 8News 12
Vendor claim Mathematical & physical sciences · OECD 1.1

Mathematics

L3Systemic transformation↑ Rising ↓ from L4 AI ×7Field ×4

Maths has the strongest AI-discovery record: in May 2026 an OpenAI model disproved Erdős’s 1946 unit-distance conjecture (a human-verified write-up by nine mathematicians incl. Alon, Gowers, Sawin), PNAS published AlphaEvolve’s 67-problem study, and a DeepMind agent resolved 9 open Erdős problems in Lean. Broad practitioner adoption and curriculum change have not happened, and openai/math saw withdrawals and push-back, so the composite is L3 (discovery scored 4).

Score 2.90Latest 2026-10-20Milestones 24News 12
Mathematical & physical sciences · OECD 1.4

Chemistry

L3Systemic transformation↑ Rising ↑ from L2 AI ×1Field ×1

Raised to L3: the 2024 chemistry Nobel went to AI structure prediction and design; retrosynthesis and ML potentials are routine; in 2026 autonomous platforms discovered new reactions and ligands (Nat. Commun. Jun & Oct 2026) and low-cost self-driving labs appeared. Day-to-day lab work is still largely manual.

Score 2.55Latest 2026-10-20Milestones 9News 12
Vendor claim Life & medical sciences · OECD 3.2

Medical imaging & pathology

L3Systemic transformation→ Steady Field ×1

Imaging is medicine's most AI-penetrated branch: radiology dominates FDA's AI device list; the MASAI RCT showed AI-supported mammography safely cut reading workload by ~44% (Lancet Oncology 2023).

Score 2.80Latest 2026-10-20Milestones 9News 12
Vendor claim Engineering & computing · OECD 1.2

Computer science (algorithms & theory)

L3Systemic transformation↑ Rising AI ×2

AI has found adopted algorithms (AlphaDev sorting merged into LLVM libc++; AlphaTensor) and improved hardness bounds (AlphaEvolve 2026); The AI Scientist appeared in Nature (Mar 2026).

Score 2.90Latest 2026-10-20Milestones 8News 5
Vendor claim Engineering & computing · OECD 1.2

Software engineering

L3Systemic transformation↑ Rising ↓ from L4

Lowered to L3: adoption is the highest of any field (Stack Overflow 2026: over 70% of respondents use AI daily), but Google’s ~75% and Anthropic’s 90%+ code shares are vendor claims and cannot alone justify L4. METR’s RCT found experienced OSS developers 19% slower in early 2025; 2026 follow-ups estimate speed-ups but with design limits, so independent productivity evidence is mixed.

Score 3.10Latest 2026-10-20Milestones 10News 12
Vendor claim Engineering & computing · OECD 2.2

Cybersecurity

L3Systemic transformation↑ Rising AI ×2

AI finds real vulnerabilities at scale: Anthropic validated 500+ high-severity bugs with Claude Opus 4.6 (Feb 2026), Microsoft FORGE contributed to 140 Windows CVEs (May–Sep 2026), TitanCA found 203 zero-days; Google saw the first likely AI-developed zero-day exploit in the wild. Close to level 4.

Score 2.80Latest 2026-10-20Milestones 9News 12
Earth & environment · OECD 1.5

Meteorology & climate science

L3Systemic transformation↑ Rising AI ×1Field ×4

AI weather models are operational: ECMWF's AIFS went operational in Feb 2025 and v2 on 12 May 2026; NOAA runs AI global models (AIGFS etc.). GraphCast, GenCast and Pangu laid the peer-reviewed groundwork.

Score 3.35Latest 2026-10-20Milestones 12News 11
Vendor claim Arts · OECD 6.4

Music

L2Local breakthroughs↑ Rising

AI music moved from lawsuits to licensing: Warner settled with Suno and Udio, Universal with Udio, and Suno launched label-licensed models (2026); IFPI issued global principles for AI recordings on official charts.

Score 1.60Latest 2026-10-21Milestones 9News 11
Mathematical & physical sciences · OECD 1.1

Statistics

L2Local breakthroughs→ Steady

Tabular foundation model TabPFN beats tuned gradient boosting on small tabular data (Nature 2025); prediction-powered inference enables valid inference with ML predictions (Science 2023). Core methods are not yet systematically rewritten.

Score 1.90Latest 2026-10-20Milestones 10News 5
Vendor claim Mathematical & physical sciences · OECD 1.3

Physics

L2Local breakthroughs↑ Rising AI ×1

Peer-reviewed results in quantum error-correction decoding (AlphaQubit, Nature 2024), autonomous law discovery (SciExplorer, PRX 2026) and particle-model building (Commun. Phys. 2026); not yet the mainstream way physics is done.

Score 1.90Latest 2026-10-20Milestones 11News 9
Contested Mathematical & physical sciences · OECD 2.5

Materials science

L2Local breakthroughs→ Steady AI ×1

GNoME predicted 2.2M crystals and MatterGen designs materials generatively (Nature 2023/2025), A-Lab synthesises autonomously; but the A-Lab paper was corrected in Jan 2026 (41/58 → 36/57), so “AI-discovered materials” claims remain contested.

Score 2.20Latest 2026-10-20Milestones 10News 8
Vendor claim Life & medical sciences · OECD 3.1

Neuroscience

L2Local breakthroughs↑ Rising Field ×1

AI enabled the adult-fly whole-brain connectome (FlyWire, Nature 2024) and speech-decoding BCIs (Nature 2023); 2026 saw many connectome foundation models, mostly preprints/benchmarks.

Score 2.20Latest 2026-10-20Milestones 10News 12
Vendor claimContested Life & medical sciences · OECD 3.1

Pharmacy & drug discovery

L2Local breakthroughs↑ Rising

AI-discovered drugs are in late-stage trials: Insilico's rentosertib Phase 2a in Nature Medicine (2025), now in Phase 3; Takeda's zasocitinib beat Sotyktu head-to-head in Phase 3. No “AI-designed” drug approved as of Oct 2026.

Score 2.20Latest 2026-10-20Milestones 10News 12
Life & medical sciences · OECD 3.2

Clinical medicine

L2Local breakthroughs↑ Rising

FDA lists 1,614 AI-enabled devices (4 Sep 2026 update); AMIE out-diagnosed clinicians in simulated consults (Nature 2025). Prospective evidence for LLMs in care is still thin.

Score 2.15Latest 2026-10-20Milestones 10News 12
Life & medical sciences · OECD 3.3

Public health & epidemiology

L2Local breakthroughs→ Steady

EVEscape forecast SARS-CoV-2 escape mutations from pre-pandemic data (Nature 2023); WHO issued LMM governance guidance in 2024. Use is mostly surveillance and analysis support.

Score 1.90Latest 2026-10-20Milestones 10News 7
Life & medical sciences · OECD 1.6

Ecology & biodiversity

L2Local breakthroughs↑ Rising

Acoustic (BirdNET) and camera-trap classifiers are routine; Europe's Biodiversa+ pilot deployed ~200 AI sensors at 70 sites, moving from pilots to networks.

Score 2.10Latest 2026-10-20Milestones 7News 6
Vendor claim Engineering & computing · OECD 2.2

Robotics & automation

L2Local breakthroughs↑ Rising

Vision-language-action models give robots some generalisation (RT-2 2023, π0 2024, Gemini Robotics 2025), but real-world reliability and deployment at scale remain unsolved.

Score 2.20Latest 2026-10-20Milestones 8News 12
Vendor claim Engineering & computing · OECD 2.7

Energy & fusion

L2Local breakthroughs↑ Rising AI ×1

Deep RL controls tokamak plasmas (Nature 2022) and AI avoids tearing instabilities (Nature 2024); DeepMind and CFS use TORAX to plan SPARC operations.

Score 1.55Latest 2026-10-20Milestones 7News 6
Contested Earth & environment · OECD 1.5

Earth sciences (seismology, geology, oceans)

L2Local breakthroughs→ Steady

Deep-learning phase picking (PhaseNet, EQTransformer) is standard for building catalogues; in 2026 AI gives aftershock risk in seconds, but individual large-quake prediction remains unreliable.

Score 2.20Latest 2026-10-20Milestones 8News 3
Earth & environment · OECD 1.5

Geography & remote sensing

L2Local breakthroughs↑ Rising

Geospatial foundation models are replacing per-task models: NASA/IBM open-sourced Prithvi; DeepMind released AlphaEarth Foundations global embeddings.

Score 2.10Latest 2026-10-20Milestones 10News 5
Social sciences · OECD 5.2

Finance

L2Local breakthroughs→ Steady

ML asset pricing (Gu, Kelly & Xiu, RFS 2020) is a mainstream empirical method; quant and risk use is widespread, while LLMs remain assistive.

Score 2.45Latest 2026-10-20Milestones 6News 12
Social sciences · OECD 5.3

Education

L2Local breakthroughs↑ Rising

RCT evidence is arriving: a Harvard physics AI tutor beat active-learning classes (Sci. Rep. 2025); a 2026 NBER two-year Khanmigo trial found ~0.06–0.08 SD/year maths gains, with low engagement.

Score 2.10Latest 2026-10-20Milestones 6News 12
Vendor claim Social sciences · OECD 6.2

Linguistics

L2Local breakthroughs→ Steady

NLLB extended neural MT to 200 languages (Nature 2024), helping low-resource documentation; LLMs are now evidence in debates on acquisition and syntax.

Score 1.90Latest 2026-10-20Milestones 9News 5
Vendor claim Arts · OECD 6.4

Visual arts & design

L2Local breakthroughs→ Steady AI ×1

AI works have entered markets and prizes: Christie's sold “Portrait of Edmond de Belamy” in 2018, and a Midjourney image won the Colorado State Fair digital-art prize in 2022; design widely uses generative tools.

Score 1.60Latest 2026-10-20Milestones 14News 6
Vendor claim Arts · OECD 6.4

Film & animation

L2Local breakthroughs↑ Rising AI ×1

Text-to-video (Sora from 2024) has entered production; the 99th Oscars rules (May 2026) say generative AI use does not disqualify a film, but acting and writing awards require human work.

Score 1.60Latest 2026-10-20Milestones 7News 12
ContestedVendor claim Engineering & computing · OECD 2.2

Electronics & chip design

L2Local breakthroughs↑ Rising

RL chip placement (AlphaChip) was used for several TPU generations (Nature 2021) but its reproducibility is disputed (CACM re-evaluation); in 2026 Synopsys pushes agentic EDA, with AMD reporting 25–40% shorter debug cycles (vendor figures).

Score 1.90Latest 2026-10-19Milestones 8News 7
Vendor claim Engineering & computing · OECD 2.3

Aerospace & mechanical engineering

L2Local breakthroughs→ Steady AI ×1

Under DARPA ACE, AI flew the X-62A in within-visual-range dogfights against a crewed F-16 (announced 2024) — a local breakthrough; design and manufacturing use is still mostly assistive.

Score 1.90Latest 2026-10-19Milestones 6News 12
Contested Social sciences · OECD 5.1

Psychology

L2Local breakthroughs→ Steady

Centaur, fine-tuned on 10M+ human choices, predicts behaviour better than classic cognitive models (Nature 2025), though evaluations show divergence from humans; AI dialogues durably reduced conspiracy beliefs (Science 2024).

Score 1.65Latest 2026-10-19Milestones 9News 5
Vendor claim Mathematical & physical sciences · OECD 1.3

Astronomy & astrophysics

L2Local breakthroughs→ Steady

ML finds exoplanet candidates and supernovae at scale (≈10,000 new TESS candidates, ApJS 2026; NASA ExoMiner++ ≈7,000), though most still need vetting and follow-up.

Score 2.45Latest 2026-10-15Milestones 9News 3
Humanities · OECD 6.1

Archaeology & classics

L2Local breakthroughs↑ Rising Field ×2

Ithaca (Nature 2022) and Aeneas (Nature 2025) restore and date inscriptions; the Vesuvius Challenge read carbonised Herculaneum papyri (2024 prize; ~1.5 m of Greek from PHerc. 1667 in 2026); AI helped find 303 new Nazca geoglyphs (PNAS 2024).

Score 1.90Latest 2026-10-15Milestones 7News 5
Contested Social sciences · OECD 5.8

Journalism & communication

L1Assistive↑ Rising

Reuters Institute DNR 2026: use of AI chatbots for news rose from 7% to 10%; UK newsrooms use AI for transcription, translation and verification, but integration is limited.

Score 0.90Latest 2026-10-21Milestones 8News 6
Vendor claim Life & medical sciences · OECD 4.1

Agricultural sciences

L1Assistive→ Steady

AI is used for genomic selection, phenotype prediction and pest ID; 2026 Nature Communications crop models are benchmark gains, with no field-validated landmark AI breeding result yet.

Score 1.30Latest 2026-10-20Milestones 7News 5
Engineering & computing · OECD 2.1

Architecture & civil engineering

L1Assistive→ Steady

Broad but shallow: RIBA's 2026 report says 74% of practices use AI on some projects, mostly general generative tools; structural engineers keep judgment central. No recognised AI-originated design breakthrough.

Score 1.25Latest 2026-10-20Milestones 7News 4
Social sciences · OECD 5.2

Economics

L1Assistive→ Steady

Stays L1 (close to L2): ML causal inference and text methods are common and a 2026 NBER paper uses an LLM workflow to reproduce and extend published work, but a 74-country Nature Human Behaviour study shows simulated LLM respondents are weak proxies for human preferences; no recognised AI-key discovery yet.

Score 1.30Latest 2026-10-20Milestones 7News 10
Social sciences · OECD 5.4

Sociology & political science

L1Assistive→ Steady

“Silicon samples” (LLM-simulated respondents, Political Analysis 2023) spark debate but reliability is doubtful (Nat. Hum. Behav. 2026); main uses are text coding and survey support.

Score 1.30Latest 2026-10-20Milestones 7News 5
Social sciences · OECD 5.5

Law

L1Assistive↑ Rising

Legal practice uses AI widely, with problems: Charlotin's database lists 2,202 decisions on AI hallucinations, Reuters counts 1,395 US cases; >60% of surveyed federal judges have used AI but only 22.4% weekly.

Score 1.00Latest 2026-10-20Milestones 7News 12
Humanities · OECD 6.1

History

L1Assistive↑ Rising

Handwritten text recognition (e.g., Transkribus) speeds up archive transcription; Schmidt Sciences funded a $10M AI-and-humanities programme in 2026, but historical interpretation remains human.

Score 1.20Latest 2026-10-20Milestones 6News 3
Vendor claim Social sciences · OECD 3.3

Sports science

L1Assistive→ Steady ↓ from L2

Lowered to L1: AI in sport is mainly tracking, video analysis and officiating aids (e.g. semi-automated offside at the 2022 World Cup); AI-key research is limited to a few tools such as TacticAI (Nat. Commun. 2024).

Score 1.45Latest 2026-10-19Milestones 10News 5
Vendor claim Humanities · OECD 6.3

Religious studies

L0Not yet transformed→ Steady ↓ from L1

Lowered to L0: in religious studies AI is mainly an object of study and an ethical topic (Rome Call 2020, encyclical Magnifica humanitas 2026); tool use is sporadic. Composite below 0.75.

Score 0.30Latest 2026-10-21Milestones 7News 6
Contested Humanities · OECD 6.2

Literature

L0Not yet transformed→ Steady ↓ from L1

Lowered to L0: isolated cases in creative writing (Akutagawa Prize 2024) and experiments (AI poetry hard to tell apart in blind tests), but no AI-key results in literary studies and no adoption data. Composite below 0.75.

Score 0.55Latest 2026-10-21Milestones 8News 5
Humanities · OECD 6.3

Philosophy

L0Not yet transformed→ Steady ↓ from L1

Lowered to L0 (not yet transformed): AI is mainly an object of philosophical study; tool use is limited to sporadic literature-review attempts and LLM experiments in experimental philosophy. Composite score below 0.75.

Score 0.30Latest 2026-10-19Milestones 7News 4

Latest progress

100 items · ● milestone ○ news · headlines in their original language

  1. The new economics of enterprise AI
    L1 EconomicsMIT Technology Review - AINews

How levels are defined

L0Not yet transformed

Composite < 0.75: only scattered use or discussion; AI has not changed methods, discovery, practice or teaching.

Reviewed every 180 days · 3 disciplines

L1Assistive

Composite 0.75–1.49: AI is an aid in parts of research or practice, with cases or surveys, but no recognised AI-key result.

Reviewed every 90 days · 8 disciplines

L2Local breakthroughs

Composite 1.5–2.49: at least one peer-reviewed/officially verified AI-key result, or one dimension at 3; routine workflow largely unchanged.

Reviewed every 90 days · 23 disciplines

L3Systemic transformation

Composite 2.5–3.49 (or ≥3.5 with any of method/discovery/adoption below 3): AI is standard infrastructure with multiple independent breakthroughs.

Reviewed every 60 days · 9 disciplines

L4AI-led

Composite ≥ 3.5 and method, discovery and adoption all ≥ 3: AI produces core results at scale, independently verified.

Review cycle: see method · 0 disciplines

How the score works

S = 0.30·method + 0.35·discovery + 0.25·adoption + 0.10·education (education scores 0 when there is no evidence; if empty, the other weights are renormalised)

Research method ×0.3Scientific discovery ×0.35Practitioner adoption ×0.25Education & curriculum ×0.1

  • Leap — 解决长期公开难题、首次超越最强人类/现有最佳方法、或改变学科常规做法,且经同行评审或独立专家/官方核验
  • Major — 顶刊/顶会成果、重要系统发布、规模化部署或政策,影响明显但局部
  • Incremental — 改进、数据集、调查、个案或早期信号

Labels

  • Vendor claimOnly the vendor’s own account; figures and claims are not independently verified.
  • ContestedPublicly challenged, withdrawn or corrected; the claim is disputed.
  • PreprintPreprint (arXiv, bioRxiv …), not yet peer-reviewed.
  • To be verifiedDate or details not yet confirmed (e.g. only year or month known).

Method & disclaimer

Levels are computed from four dimension scores; vendor-claimed figures are not independently verified; see impactRule for breakthrough ratings.

  • Link checked (HTTP 200)
  • Site blocks scripts; DOI title and date checked via Crossref
  • Site blocks scripts; checked by hand
  • From RSS/API feed; link is the original
  • Link not yet checked

News are matched by discipline keywords from the site’s news collection and other feeds; 35 items also appear in AI News. Data as of 2026-10-22; machine-readable: /api/v1/disciplines.json

Data updated: AI × disciplines(UTC+8)