// AI news · 2026-10-31 · WIRED
AI Agent Performs Brain Injection in Live Mouse
An AI agent successfully performed a brain injection in a live mouse using Exin Therapeutics' custom surgical setup.
Published 2026-10-31 18:00 (Beijing time)Source WIREDAuto-summarised, fact-checked against source
01Summary
The agent selected a gene therapy from 19 options and controlled needle placement and delivery parameters. Claude Opus 5.5 refused to proceed due to safety concerns, while Claude Sonnet 5 agreed. A technical glitch caused coordinate errors, and the agent could not modify code due to restrictions, requiring a second AI to fix it. Human oversight remains essential for animal experiments.
Summarised from the original article by an open-source model, then checked automatically: every number and English name must appear in the source. The original article is authoritative.
02Key points
- AI agent completed gene therapy injection in live mouse brain.
- Claude Opus 5.5 refused injection; Sonnet 5 proceeded instead.
- Coordinate error occurred; agent could not self-correct due to access restrictions.
- Human supervision remains critical for animal experiments.
03Source
An AI Agent Injected Drugs Into a Live Mouse’s Brain
WIRED · published 2026-10-31 18:00 Beijing time
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